Phthalide

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

other: OECD 104

Principles of method if other than guideline:

dynamic under nitrogen

GLP compliance:

no

Type of method:

dynamic method

Key result

Boiling pt.:

291.56 °C

Atm. press.:

1 013.25 hPa

Remarks on result:

other: extrapolation from the vapour pressure curve.

Results:

Temperature [°C]	Vapour pressure (measurement) [hPa]	Vapour pressure (calculation^b)) [hPa]	Aberration [%]
93.31	1.00	1.000	0.01
105.18	1.95	1.949	0.03
113.87	3.08	3.081	-0.05
123.97	5.09	5.091	-0.03
131.06	1.77	7.115	-0.07
138.91	10.12	10.141	-0.21
155.13	20.17	20.084	0.43
165.55	30.24	30.179	0.20
179.45	50.33	50.181	0.30
189.44	70.42	70.714	-0.42
200.37	10.39	100.912	-0.52
223.3	200.6	200.38	0.11
238.1	300.4	300.24	0.05
258.3	501.0	499.70	0.26
272.8	701.5	701.13	0.05
289.7	1012.8	1014.46	-0.16
291,56	-	1013.25	-

The regression of the results leads with a mean deviation of 0.166 % to the following equation:

ln(p/hPa) = 10.0846 - 2855.25 / (215.84 + t/°C)

The vapour pressure at 20 °C, 25 °C and 50°C was not calculated from the regression equation, since the melting point is on the regression equation

The normal boiling temperature was obtained by intrapolation/extrapolation from the vapour pressure curve.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

no guideline available

Principles of method if other than guideline:

Secondary literature source no data about the method was available.

GLP compliance:

not specified

Type of method:

other: no data

Boiling pt.:

290 °C

Remarks on result:

other: Value from generally accepted authoritative handbook. No data available for atm. pressure.

Description of key information

The value for the boiling point was determined in an experimental study performed equivalent or similar to OECD 104 (BASF AG, 2001). The boiling point of phthalide was found to be 291.56 °C at 1013.25 hPa.

In addition, the boiling point of phthalide was reported to be 290 °C according to the Knovel Critical Tables (2nd Edition).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

292 °C