Registration Dossier
Registration Dossier
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EC number: 204-024-4 | CAS number: 113-24-6
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- No guideline is required for QSAR.
- GLP compliance:
- no
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.95 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: A standard duration of 28 d for chronic studies is assigned.
- Conclusions:
- QSAR model IRFMN 1.0.0 predicts a NOEC of 3.95 mg/L for daphnia for sodium pyruvate based on 6 similar compounds.
Reliability 2/3
Reference
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- 3.95 mg/L
Additional information
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