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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 September 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Fully documented study run under GLP and according to international guidelines.
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
static method
Key result
Temp.:
20 °C
Vapour pressure:
7 263 Pa
Temp.:
25 °C
Vapour pressure:
9 273 Pa
Transition / decomposition:
no

Table 1        Measurement Values

1. Determination
increasing temperature

2. Determination
decreasing temperature

Temp. in °C

Pressure in hPa

Temp. in °C

Pressure in hPa

20.8

74.4

51.7

303.2

24.4

88.6

42.5

208.5

27.4

103.5

37.6

169.3

29.1

113.0

33.6

140.6

33.4

138.8

29.6

115.8

33.0

136.0

26.2

97.9

41.6

199.4

23.6

86.2

46.9

246.3

22.1

80.2

54.5

328.8

-

-

54.6

331.0

-

-

 

From the measured values for the increasing and for the decreasing temperature, log P and 1/T were calculated and log P (in log Pa) against 1/T (in 1/K) was plotted.

The regression curve with slope B, intercept A and correlation r was calculated. From the values of these parameters, vapour pressures at 20.0 °C and at 25.0 °C were calculated with: Log P = (B * 1/T) + A.

The parameters for the linear regression of the values are presented in the following table:

Table 2     Linear Regression Parameters

Parameter

Value

Slope

-1854.550616

Intercept

10.18740179

Correlation coefficient r

-0.999644229

 

Using the equation which is stated in chapter 8.2, vapour pressure at ambient temperature and boiling point were calculated as:

Table 3     Calculated Values for Vapour Pressure

Parameter

Value

Unit

Vapour Pressure (20 °C)

7263

Pa

Vapour Pressure (25 °C)

9273

Pa

 

Conclusions:
Vapour pressures of 7263 Pa at 20 °C and 9273 Pa at 25 °C were determined for reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA).
Executive summary:

The vapour pressure of reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methyl­propan-2-ol (TBA) was determined using the static method.

Vapour pressures of 7263 Pa at 20 °C and 9273 Pa at 25 °C were determined.

These values were calculated from the regression of 18 individual measurements.

Description of key information

Vapour pressures of 7263 Pa at 20 °C and 9273 Pa at 25 °C were determined.

Key value for chemical safety assessment

Vapour pressure:
7 263 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the test item reaction mass of 2,2'-oxybisbutane (DSBE), DIPE, SBA and 2-methylpropan-2-ol (TBA) being a representative sample for "2-propanol and 2-butanol production, distn. residues" was calculated as 7263 Pa at 20.0 °C, and 9273 Pa at 25 °C. These values show good correspondence with the measured values in this temperature range: at 20.4 °C, 7440 Pa were measured, at 24.4 °C 8860 Pa and at 26.2 °C, 9790 Pa were measured.

No deviations between the measured values at increasing and at decreasing temperatures were detected. No observations were made which might cause doubts concerning the validity of the study outcome and therefore the study is considered valid.