Registration Dossier
Registration Dossier
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EC number: 223-395-3 | CAS number: 3874-54-2
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study according to international accepted guidelines, but not GLP compliant.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- 4-chloro-4'-fluorobutyrophenone
- EC Number:
- 223-395-3
- EC Name:
- 4-chloro-4'-fluorobutyrophenone
- Cas Number:
- 3874-54-2
- Molecular formula:
- C10H10ClFO
- IUPAC Name:
- 4-chloro-1-(4-fluorophenyl)butan-1-one
- Test material form:
- other: liquid
- Details on test material:
- Test item: 4-Chloro-4’-fluorobutyrophenoneCAS number: 3874-54-2EC number: 223-395-3Molecular formula: C10H10ClFOMolecular weight: 200.64 g/molSupplier: Sigma-AldrichBatch number STBD6247VPhysical state: liquidColour: Dark yellowStorage: cool, dry place in a tightly closed container
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 0.111 g/L
- Temp.:
- 30 °C
- pH:
- 2.51 - 2.53
- Remarks on result:
- other: 24-hour result
- Details on results:
- The test item is very unstable in aqueous solution. The insoluble particles disappeared from the emulsion during 48 hours while the concentration of the test item decreased in the solution.Because of fast degradation, the results of first measurement (after 24 h) were used only for determination of water solubility.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
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