Registration Dossier
Registration Dossier
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EC number: 201-143-3 | CAS number: 78-79-5
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Adequacy of study:
- disregarded due to major methodological deficiencies
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Gould E (1959). Mechanism and Structure in Organic|Chemistry. Holt, Reinhart and Winston, New York, NY, USA.
- Title:
- No information
- Author:
- Harris J (1982). Rate of Hydrolysis. In: Handbook of|Chemical Property Estimation Methods. Chapter 7. Edited by|WJ Lyman, WF Reehl and DH Rosenblatt. McGraw-Hill Book|Company, New York, NY, USA.
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- IUCLID4 Test substance: other TS: Isoprene
Constituent 1
Results and discussion
Dissipation DT50 of parent compoundopen allclose all
Any other information on results incl. tables
Hydrolysis
of an organic molecule can occur when a molecule (R-X) reacts with water
(H2O) to form a new carbon-oxygen bond after the carbon-X bond is
cleaved. Mechanistically, this reaction is referred to as a nucleophilic
substitution reaction, where X is the leaving group being replaced by
the incoming nucleophilic oxygen from the water molecule. The leaving
group, X, must be a molecule other than carbon because for hydrolysis to
occur, the R-X bond cannot be a carbon-carbon bond. This reaction
differs from other reactions with water such as hydration of carbonyls
that can lead to the formation of an alcohol beginning with the transfer
of a proton from the water to an alkene. However, water by itself is too
weak an acid to transfer a proton in the absence of a strong acid, which
could effect such an acid catalysed electrophilic addition.
Thus, hydrocarbons such as alkenes are not subject to hydrolysis under
conditions typically found within the environment and therefore, this
fate process will not contribute to the degradative loss of
2-methyl-2-butene from the environment.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
