Registration Dossier
Registration Dossier
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EC number: 204-634-0 | CAS number: 123-54-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96 h acute aquatic toxicity of 2,4-pentanedione to fish ranged from 60.1 mg/l to 204 mg/l depending on the species used
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 104 mg/L
Additional information
The acute aquatic toxicity of 2,4-pentanedione to fish has been investigated in several species of fresh water fish. In flow -through studies with analytical monitoring the material showed a minimum 96 h LC50 of 60.1 mg/l in the bluegill (Lepomis macrochirus) (C.I. 50.3 – 71.8 mg/l) and a maximum 96 h LC50 of 204 mg/l in the mosquito fish (Gambusia affinis) (Thurston et al. 1985, Brooke et al. 1984).[modified from OECD SIDS Dossier]
The most valid and best described test were performed on Pimephales promelas by Brooke and Geiger et al in 1984 and 1985 showing LD50s of 104 and 175 mg/l. Test method and test This is in good compliance with the test performed by Phipps et al. (155 mg/l).
Therefore the lowest LD50 of these tests is used as a key value.
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