Registration Dossier
Registration Dossier
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EC number: 203-870-1 | CAS number: 111-44-4
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Remarks:
- no data
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Information from data base, no study details were provided.
Data source
Reference
- Reference Type:
- other: Internet data base
- Title:
- GESTIS-Stoffdatenbank Gefahrstoffinformationssystem der Deutschen Gesetzlichen Unfallversicherung
- Author:
- IFA Institut für Arbeitschutz der Deuitschen Gesetzlichen Unfallversicherung
- Year:
- 2 004
- Bibliographic source:
- www.dguv.de/ifa/de/gestis/stoffb/index.jsp
Materials and methods
- Principles of method if other than guideline:
- no information. Information obtained from dermal tests?
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Bis(2-chloroethyl) ether
- EC Number:
- 203-870-1
- EC Name:
- Bis(2-chloroethyl) ether
- Cas Number:
- 111-44-4
- Molecular formula:
- C4H8Cl2O
- IUPAC Name:
- 1-chloro-2-(2-chloroethoxy)ethane
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
In vivo
Results
- Remarks on result:
- other: The handbook contains following statement: "Entsprechend dermalen Tests an Kaninchen und Meerschweinchen ist die hautreizende Wirkung gering." Based on dermal tests with rabbit and guinea pig, the skin irritation is low.
Applicant's summary and conclusion
- Executive summary:
The data bank GESTIS contains following statement:
Entsprechend dermalen Tests an Kaninchen und Meerschweinchen ist die hautreizende Wirkung gering. Based on experience from dermal tests, the skin irritating potential of BCEE is low.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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