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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
DPIM: HEP000
Author:
Richard J. Lewis, Sr.
Year:
2007
Bibliographic source:
SAX (Sax's Handbook of Dangerous Industrial Materials)Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al., Moscow, USSR.:  , Centre of International Projects, GKNT, 1982, 100.
Reference Type:
other: Authoritative data base
Title:
GCID 82957
Year:
2011
Bibliographic source:
ACToR (Aggregated Computational Toxicology Resource);Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.
Reference Type:
review article or handbook
Title:
RTECS Number : MO1955000
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances); 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,100,1982

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is from RTECS, ACToR and SAX.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Piperazine adipate
EC Number:
205-569-0
EC Name:
Piperazine adipate
Cas Number:
142-88-1
Molecular formula:
C6H10O4.C4H10N2
IUPAC Name:
piperazine adipate
Test material form:
solid: crystalline
Details on test material:
- Name of test material : piperazine adipate
- Molecular formula : C6H10O4.C4H10N2
- Substance type: Organic
- Physical state: Solid

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 640 mg/kg bw
Based on:
test mat.
Remarks on result:
other: Details of toxic effects not reported other than lethal dose value.

Applicant's summary and conclusion

Conclusions:
Oral toxicity (LD50) by intraperitoneal route for piperazine adipate was examined in mouse at dose concentration of 1640 mg/kg .Details of toxiceffects not reported other than lethal dose value.
Executive summary:

Oral toxicity (LD50) by intraperitoneal route for piperazine adipate was examined in mouse at dose concentration of 1640 mg/kg .Details of toxiceffects not reported other than lethal dose value.