Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term toxicity to fish

The lethal concentration (LC50) for piperazine adipate for Oncorhynchus mykiss at 96 hours is estimated to be 134.66 mg/L. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.

Long-term toxicity to fish

According to column I of annex IX , Long-term toxicity testing on fish need not to be conducted as information on short term toxicity effect is already provided as part of Annex VIII requirements. Therefore this study was considered to be waived.

Short-term toxicity to aquatic invertebrates

The effective concentration (EC50) for piperazine adipate for Daphnia magna at 48 hours is estimated to be 201.06 mg/L for intoxication effect. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.

Long-term toxicity to aquatic invertebrates

According to column I of annex IX ; Long-term toxicity testing on invertebrate (species : Daphnia) need not to be conducted as information on short term toxicity to aquatic invertebrates is already provided as a part of Annex VII requirements. Therefore this study was considered for waiver.

Toxicity to aquatic algae and cyanobacteria

The effective concentration (EC50) for piperazine adipate for Pseudokirchneriella subcapitata at 72 hours is estimated to be 119.68 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation.

Toxicity to microorganisms

The growth inhibition concentration (IGC50) for piperazine adipate for Tetrahymena pyriformis at 48 hours is estimated to be 916.19 mg/L for effect on growth. Based on this value it can be concluded that piperazine adipate is not toxic to aquatic environment based the criteria given by CLP regulation