Registration Dossier
Registration Dossier
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EC number: 605-539-0 | CAS number: 169115-74-6
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
No classification with regard to carcinogenicity is required.
Additional information
No carcinogenicity studies are available for carbamic acid, (2-hydroxypropyl)-, compound with 1-amino-2-propanol (1:1) or the immediate cleavage product 1-amino-2-propanol (justifcation for read-across see IUCLID chapter 13). However, both substances did not show any mutagenic effects in several mutagenicity tests and the cleavage product 1-amino-2-propanol was shown to be of low toxicity in repeated dose toxicity studies and no hyperplasia or pre-neoplastic lesions were observed in any available study.. Therefore, a carcinogenic potential of carbamic acid, (2-hydroxypropyl)-, compound with 1-amino-2-propanol (1:1) can be considered unlikely.
Justification for selection of carcinogenicity via oral route endpoint:
No carcinogenicity study is required since the substance is not a mutagen and no hyperplasia or pre-neoplastic lesions were observed in the available study.
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