Registration Dossier
Registration Dossier
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EC number: 605-539-0 | CAS number: 169115-74-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of algae was measured and showed an ErL10 of 26.1 mg/L and an ErL50 of 149 mg/L. A NOEL [r] of 25 mg/L and a LOEL [r] of 50 mg/L were calculated.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 149 mg/L
- EC10 or NOEC for freshwater algae:
- 26.1 mg/L
Additional information
In order to test acute toxicity to algae 'Desmodesmus subspicatus' of the substance was exposed to the test solution of five nominal concentrations (6.3, 12.5, 25, 50 and 100 mg/L) and blank control solution for a period of 72 hours under static conditions. The cell densities were measured at 24 hours intervals. Inhibition of the algal population was measured as reduction in growth rate relative to control cultures grown under identical conditions. The measured concentrations confirmed that deviation from the nominal concentrations was less than 30 %. An ErL10 of 26.1 mg/L and an ErL50 of 149 mg/L. A NOEL [r] of 25 mg/L and a LOEL [r] of 50 mg/L were calculated. The results are expressed in terms of Effective Loadings (EL).
The pH value of the control after 72 hours increased by more than1.5 pH units. This increase is not regarded as relevant as all validity criteria were met.
As the test item is a multi-constituent and no information about the correlation between molecular weight and the structural formula of the test item are available, Water Accommodated Fractions (WAFs) were used to test effects at different effective loadings and no specific analysis was performed. The content of the test item during the exposure period was verified by DOC determination. This toxicity study fulfills the guideline requirements for the acute algae study.
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