Registration Dossier

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: scientifically acceptable

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report Date:
1988

Materials and methods

Test guideline
Guideline:
other: measured
GLP compliance:
no
Type of method:
other: (visual observation of the saturation point)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
Name of test material (as cited in study report): caffeine
Analytical purity: unrefined product

Results and discussion

Water solubility
Water solubility:
18.7 g/L
Temp.:
16 °C

Any other information on results incl. tables

Temperature   caffeine
°C % (g/100g water)
10.0 1.35 (extrapolated value)
16.0 1.87
28.0 3.19
44.1 7.67
58.7 15.22
64.9 21.41
79.0 35.41
83.9 46.84
100.3 81.0 (extrapolated value)

Applicant's summary and conclusion