Registration Dossier
Registration Dossier
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EC number: 200-362-1 | CAS number: 58-08-2
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer revuiewed data base
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Lange's Handbook of Chemistry.
- Author:
- Dean, J.A.
- Year:
- 1 985
- Bibliographic source:
- 13 ed. New York, NY: McGraw-Hill Book Co., p. 526. cited in HSDB 21 Sep 2006, and SRC PhysProp Database, query date 31 Jul 2007
Materials and methods
Test guideline
- Guideline:
- other: measured
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Caffeine
- EC Number:
- 200-362-1
- EC Name:
- Caffeine
- Cas Number:
- 58-08-2
- Molecular formula:
- C8H10N4O2
- IUPAC Name:
- 1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
- Details on test material:
- name of test material (as cited in study report): caffeine
Analytical purity: pure
Constituent 1
Results and discussion
- Dissociating properties:
- yes
Dissociation constant
- pKa:
- 10.4
- Temp.:
- 40 °C
- Remarks on result:
- other: Acid-base constant:
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
