Esterification products of alkenylsuccinic anhydride and 2-dialkylaminoethanol

Solubility in organic solvents / fat solubility

Link to relevant study record(s)

Reference

Endpoint:

solubility in organic solvents / fat solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14th January 1993 to 18th May 1994

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: EU Method A.7

Deviations:

not applicable

GLP compliance:

yes

Medium:

standard fat

Temp.:

37 °C

Remarks on result:

not determinable

Remarks:

The test material was miscible in standard fat in all proportions tested (between 2.2 and 3180 g/100 g fat)

Test substance stable:

yes

Table 1: Results from run 1, with 9.64 g of standard fat

Test material added (g)	Test material concentration (g/100 g fat)	Observations
0.21	2.18	Miscible
0.49	5.08	Miscible
0.87	9.02	Miscible
2.72	28.2	Miscible
3.69	38.3	Miscible
4.53	47.0	Miscible
5.96	61.8	Miscible
7.07	73.3	Miscible
7.99	82.9	Miscible
10.39	108	Miscible
13.38	139	Miscible
The test substance was shown to be miscible with standard fat between 2.2 and 139 g/100 g.

 

Table 2: Results from run 2, with 10.18 g of test material

Standard Fat Added (g)	Test material concentration (g/100 g fat)	Observations
0.21	2.18	Miscible
0.49	5.08	Miscible
0.87	9.02	Miscible
2.72	28.2	Miscible
3.69	38.3	Miscible
4.53	47.0	Miscible
5.96	61.8	Miscible
7.07	73.3	Miscible
7.99	82.9	Miscible
10.39	108	Miscible
13.38	139	Miscible
The test substance was shown to be miscible with standard fat between 82.5 and 3180 g/100 g fat. The overall range over which the test substance was shown to be miscible with standard fat was therefore 2.2 to 3180 g/100 g fat.

 

 

Conclusions:

Under the conditions of the tes, the test material was found to be miscible with standard fat in all proportions tested (between 2.2 and 3180 g/100 g fat).

Executive summary:

The solubility of the test material in standard fat was determined in a study conducted in accordance with OECD 116 and EU Method A.7. The test material was mixed with standard fat at 37 °C to attempt to produce a saturated solution. This did not occur, and a further study showed that the test material was miscible with standard fat in all proportions tested (between 2.2 and 3180 g/100 g fat).

Description of key information

The solubility of the test material in standard fat was determined in a study conducted in accordance with OECD 116 and EU Method A.7. The test material was mixed with standard fat at 37 °C to attempt to produce a saturated solution. This did not occur, and a further study showed that the test material was miscible with standard fat in all proportions tested (between 2.2 and 3180 g/100 g fat).