Registration Dossier
Registration Dossier
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EC number: 287-370-9 | CAS number: 85480-89-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 h EC50 510 mg active acid/L, D. magna, reliability 2 (read-across from EDTMP acid)
96 h LC50 >340 mg active acid/L, C. marinus, reliability 2
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 510 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 340 mg/L
Additional information
No data are available with the registered substance; however, reliable data are available with the parent substance EDTMP acid (CAS 1429-50-1).
A 48 h EC50 value of 510 mg active acid/L has been determined for the effects of EDTMP acid on the immobility of the freshwater flea Daphnia magna. The results should be treated with caution since the authors report that the mortalities seen are an effect of the pH of the test medium, rather than a reflection of true toxicity. However, the results indicate that the substance is of low short term toxicity to aquatic inverterbates.A 96 h LC50 value of >340 mg active acid/l has been reported for the effects of the registered substance EDTMP xCaxNa on the mortality of the marine shrimp Chaetogammarus marinus based on nominal concentrations.
A 96 h EC50 value of 58 ppm, equivalent to 70 mg active acid/L, has been determined for the effects of the test substance on shell deposition of the eastern oyster Crassostrea virginica. This test measures shell growth of the organisms, a sub-lethal endpoint, and is thus more sensitive than the standard invertebrate organisms test. The shell deposition is dependant on nutrient availability, however phosphonates have complexing properties and it is therefore likely that shell growth was inhibited due to a lack of bioavailable nutrients, even though the study was conducted under flowthrough conditions and the results should not be interpreted as inherent toxicity effects.
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