Registration Dossier
Registration Dossier
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EC number: 223-772-2 | CAS number: 4065-45-6
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Justification for type of information:
- Experimental tests performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- The test was conducted to determine the solubility range for which 0.1 gm of substance was dissolved in different solvents like acetone, acetonitrile, methanol, ethanol, toluene and Dimethylformamide (DMF).
- GLP compliance:
- no
- Key result
- Medium:
- methanol
- Solubility:
- > 200 - < 1 000 mg/L
- Temp.:
- 26.7 °C
- Key result
- Medium:
- ethanol
- Solubility:
- > 200 - < 1 000 mg/L
- Temp.:
- 26.7 °C
- Key result
- Medium:
- dimethylformamide
- Solubility:
- > 100 - < 200 mg/L
- Temp.:
- 26.7 °C
- Key result
- Medium:
- acetone
- Solubility:
- < 1 mg/L
- Temp.:
- 26.7 °C
- Key result
- Medium:
- acetonitrile
- Solubility:
- < 1 mg/L
- Temp.:
- 26.7 °C
- Key result
- Medium:
- toluene
- Solubility:
- < 1 mg/L
- Temp.:
- 26.7 °C
- Test substance stable:
- yes
- Details on results:
- The solubility of sulisobenzone in acetone, acetonitrile and toluene was found to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was found to be in the range of 200 – 1000mg/l and DMF was found to be in the range of 100-200mg/l, respectively at 26.7 °C.
- Conclusions:
- The solubility of test chemical in acetone, acetonitrile and toluene was determined to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was determined to be in the range of 200 – 1000mg/l and DMF was determined to be in the range of 100-200mg/l, respectively at 26.7 °C.
- Executive summary:
The solubility of test chemical in acetone, acetonitrile and toluene was determined to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was determined to be in the range of 200 – 1000mg/l and DMF was determined to be in the range of 100-200mg/l, respectively at 26.7 °C.
Reference
The solubility of sulisobenzone in acetone, acetonitrile and toluene was found to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was found to be in the range of 200 – 1000mg/l and DMF was found to be in the range of 100-200mg/l, respectively at 26.7 °C.
Description of key information
The solubility of test chemical in acetone, acetonitrile and toluene was determined to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was determined to be in the range of 200 – 1000mg/l and DMF was determined to be in the range of 100-200mg/l, respectively at 26.7 °C.
Key value for chemical safety assessment
- Solubility in organic solvents at 20°C:
- 200 mg/L
Additional information
The solubility of test chemical in acetone, acetonitrile and toluene was determined to be lesser than 1mg/l, whereas the solubility value in methanol and ethanol was determined to be in the range of 200 – 1000mg/l and DMF was determined to be in the range of 100-200mg/l, respectively at 26.7 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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