Registration Dossier
Registration Dossier
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EC number: 200-279-0 | CAS number: 56-54-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The LC50 of the read across substance quinidine sulphate for Artemia salina was determined in saltwater for 24 h. The LC50 for Artemia salina is 154.63 mg/L. According to this, the LC50 of quinidine is 118.73 mg/L. The LC50 of the read across substance quinidine sulphate for Daphnia magna was determined in fresh water for 24 h and 48 h. The EC50 of quinidine sulphate for Daphnia magna is 33.67 mg/L and 46.7, respectively. According to this, the EC50 of quinidine is 25.85 mg/L for 24 h and 40.57 mg/L for 48 h.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 25.8 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 118.73 mg/L
Additional information
In this publication of Calleja, 1994 the EC50 of quinidine sulphate for Daphnia magna as well as LC50 for Brachionus calyciflorus and Streptocephalus proboscideus were determined in fresh water for 24 h according to OECD guideline. The EC50 of quinidine sulphate for Daphnia magna is 33.67 mg/l. According to this, the EC50 of quinidine is 25.85 mg/L. The LC50 of quinidine sulphate for Brachionus calyciflorus is 4.90 mg/l and the LC50 for Streptocephalus proboscideus is 4.64 mg/l. According to this, the LC50 of quinidine for Brachionus calyciflorus is 3.76 mg/L and the LC50 for Streptocephalus proboscideus is 3.56 mg/l. Furthermore, in the publication of Lilius, 1994 the EC50 of the read across substance quinidine sulphate for Daphnia magna (Age < 24 h) was determined according to OECD guideline in freshwater for 24 h. The EC50 forDaphnia magnais 44.81 mg/L (0.06 mM). According to this, the EC50 of quinidine is 34.4 mg/L. The LC50 of the read across substance quinidine sulphate for Artemia salina was determined in saltwater for 24 h. The LC50 of quinidine sulphate for Artemia salina is 154.63 mg/l. According to this, the LC50 of quinidine is 118.73 mg/L.
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