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Diss Factsheets
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EC number: 806-451-7 | CAS number: 42532-60-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
C4 F-isonitrile is hydrolytically active when brought into contact with water. Aquatic toxicity testing was done on the hydrolysis product perfluoroisopropylamide. All key aquatic toxicity studies were performed in accordance with internationally-accepted test guidelines and are Good Laboratory Practice (GLP) compliant. As such, these results are considered reliable without restrictions. The results are suitable for purposes of Risk Assessment, Classification & Labeling, and PBT Analysis. Two non-GLP range finding studies were performed for algae and invertebrates. All aquatic toxicity results are reproduced in the table below.
Table 1. Test Results
Species |
Endpoint |
Concentration (mg/L) |
Result Parameter |
Reliability (Klimisch) |
Fish (Gobiocypris rarus) |
96-hour LC50 |
>127 (equivalent to 100 mg/L parent) |
mortality |
1 |
Invertebrate (Daphnia magna) Invertebrate (Daphnia magna) |
48-hour EC50 48-hour EC50 RF* |
>100 >100 |
immobilization mortality |
1 2 |
Algae (Pseudokirchneriella subcapitata) Algae (Pseudokirchneriella subcapitata) |
72-hour EC50
72-hour EC50 RF* |
>100 >100 100 |
growth rate cell number |
1 2 |
Activated sludge | 3 -hour EC50 | >1000 | respiration | 1 |
RF* indicates the study was a non-GLP method, range finding test
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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