Registration Dossier
Registration Dossier
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EC number: 941-319-3 | CAS number: -
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: test procedure in accordance with the European Pharmacopoeia
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: European Pharmacopoeia (2.9.38: stirring method)
- Deviations:
- no
- Type of method:
- sieving
Test material
- Reference substance name:
- Esterification products of Grape seeds, Vitis vinifera L. (Vitaceae), extract with hexadecanoyl chloride
- EC Number:
- 941-319-3
- Molecular formula:
- Unknown (Substance of Unknown or Variable Composition)
- IUPAC Name:
- Esterification products of Grape seeds, Vitis vinifera L. (Vitaceae), extract with hexadecanoyl chloride
- Test material form:
- solid: particulate/powder
1
Results and discussion
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- ca. 100 µm
- Distribution:
- >= 71.3 - <= 90.6 %
- No.:
- #2
- Size:
- ca. 180 µm
- Distribution:
- >= 69 - <= 96.3 %
- No.:
- #3
- Size:
- ca. 200 µm
- Distribution:
- >= 76.3 - <= 84 %
- No.:
- #4
- Size:
- ca. 500 µm
- Distribution:
- >= 51.3 - <= 80.4 %
Applicant's summary and conclusion
- Conclusions:
- According to the study results Palmitoyl grape seed extract is a coarse powder for which about 50 to 80% pass through a 500 micron sieve.
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