Esterification products of Grape seeds, Vitis vinifera L. (Vitaceae), extract with hexadecanoyl chloride

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

dynamic method

Test material

Test material information

1

Reference substance name:

Esterification products of Grape seeds, Vitis vinifera L. (Vitaceae), extract with hexadecanoyl chloride

EC Number:

941-319-3

Molecular formula:

Unknown (Substance of Unknown or Variable Composition)

IUPAC Name:

Esterification products of Grape seeds, Vitis vinifera L. (Vitaceae), extract with hexadecanoyl chloride

Test material form:

solid: particulate/powder

Results and discussion

Boiling point

Key result

Boiling pt.:

>= 311.3 - <= 312.9 °C

Decomposition:

yes

Decomp. temp.:

ca. 170 °C

Remarks on result:

other: Therefore, no boiling point of the test item Palmitoyl grape seed extract could be determined because of decomposition of the test item at >170 °C.

Applicant's summary and conclusion

Conclusions:

According to attached study report, no boiling point of the test item Palmitoyl grape seed extract could be determined because of decomposition of the test item at >170 °C.

Executive summary:

To determine the normal boiling point of the Palmitoyl grape seed extract, two methods were considered: The Siwoloboff method and the dynamic method. As the colour of the test item was too dark, the Siwoloboff method was not applicable. Two experiments were performed using the dynamic method. At approx. 169 (first determination) and 168 °C (second determination) bubbles on the surface was visible, which vanish after a short while. A colourless condensate could be observed before boiling started. Boiling indicated by pumping Cottrell pump was observed at 311.3 °C (first determination) and 312.9 °C (second determination) while the highest temperature measured in the sample was 350 °C (first determination and second determination) which settled down at 345 °C. The thermometer in the Cottrell pump showed a lower temperature than the temperature in the sample. If a liquid boils, the measured temperatures of the thermometers should be similar. Therefore, the temperature difference between the thermometers is a sign of decomposition. After cooling down, the test item appeared as a black mass, which indicated decomposition during the experiment, as well. Regarding the observations of the pre-test decomposition did not take place until 167 °C. Therefore, it can be believed that the appearing colourless condensate may be the start of decomposition of the test item. However, the temperature of initial decomposition of the test item cannot be determined using this method. Therefore, no boiling point of the test item Palmitoyl grape seed extract could be determined because of decomposition of the test item at >170 °C. No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.