Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature Original reference not yet available

Data source

Reference
Title:
No information
Author:
RTECS; Registry of toxic effects of chemical substances;|NIOSH (1997)

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-hydroxypropiononitrile
EC Number:
203-704-8
EC Name:
3-hydroxypropiononitrile
Cas Number:
109-78-4
Molecular formula:
C3H5NO
IUPAC Name:
3-hydroxypropanenitrile
Constituent 2
Reference substance name:
Ethylene cyanohydrin
IUPAC Name:
Ethylene cyanohydrin
Details on test material:
Purity of TS: no data

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
500 mg/kg bw

Applicant's summary and conclusion