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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed according to current OECD-Guideline and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
4-methanesulfonyl-2-nitrobenzoic acid
EC Number:
601-017-1
Cas Number:
110964-79-9
Molecular formula:
C8 H7 N1 O6 S1
IUPAC Name:
4-methanesulfonyl-2-nitrobenzoic acid

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
Sampling times: 0, 48, 96 hours

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Test conditions

Hardness:
44.7 mg/L CaCO3
Test temperature:
11.7-12.9 C
pH:
5.23-7.64
Dissolved oxygen:
6.2-10.2 mg/L
Nominal and measured concentrations:
Mean measured concentration was 100 % of the nominal concentration of 100 mg/L.

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 120 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
120 mg/L
Nominal / measured:
meas. (geom. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The nominal 96 hour NOEC of NMSBA, based on mortality and symptoms of toxicity, was considered to be = 120 mg/L.