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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated (Japanese)

Data source

Reference
Title:
No information
Author:
Mori T 1980. Okayama Igakkai Zasshi 92:1085-1089

Materials and methods

Principles of method if other than guideline:
The effect of mono-, di, tri, and tetra-chlorinated benzene on mitochondrial oxidative phosphorylation was determined by in vitro method. Endpoint study record was created to contribute to the overall results.
GLP compliance:
no
Remarks:
GLP compliance was not mandatory at the time of the study

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Endpoint study record was created to contribute to the overall results.

The respiratory control index decreased with increase in the number of chlorine and with increase in the concentration of chlorinated benzene.

Decrease in respiratory control index was in the order of ortho> meta> para-dichlorobenzenes. There were differences between isomers.

Applicant's summary and conclusion