Registration Dossier
Registration Dossier
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EC number: 235-402-7 | CAS number: 12217-80-0
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
The available information suggests that absorption of the test substance will primarily take place in the gastrointestinal tract following oral ingestion. Once absorbed, in all likelihood the substance would be distributed in the serum and excreted via the urine and faeces albeit biliary excretion may be a secondary (minor) route of excretion.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
The absorption, distribution, metabolism and excretion of FAT 36152/M TE have been predicted based on the following information:
FAT 36152/M TE absorption was indicated via the gastro-intestinal tract following oral gavage administration.
FAT 36152/M TE no absorption was indicated via the skin or ocular routes of exposure.
FAT 36152/M TE no uptake via inhalation is anticipated on the basis of the low vapour pressure value and low inhalable particle size which indicated almost all inhaled particles would be cleared in the oral/nasal region and subsequently swallowed with the mucus.
FAT 36152/M TE based on the available evidence including single oral dose and repeated oral dose reproductive screening studies that the test item and/or its predicted metabolites to have limited toxic potential when absorbed through the gastro-intestinal tract.
Excretion of FAT 36152/M TE and any of its predicted metabolites is expected to be from urine and faeces.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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