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EC number: 617-849-3 | CAS number: 86404-04-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2,5-dihydrofuran-2-one
- EC Number:
- 617-849-3
- Cas Number:
- 86404-04-8
- Molecular formula:
- C8H12O6
- IUPAC Name:
- (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2,5-dihydrofuran-2-one
- Details on test material:
- Name of test material (as cited in study report): Ethyl Ascorbic acid
Physical state: White to very pale yellow crystalline powder
Test item storage: In freezer (≤ -15°C) desiccated
Stability: Stable under storage conditions until 21 April 2018 (retest date)
Constituent 1
Results and discussion
Boiling point
- Decomposition:
- yes
- Decomp. temp.:
- > 250 °C
- Remarks on result:
- other: Reaction and/or decomposition of the test item was observed starting at 250 °C. Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.
Any other information on results incl. tables
Results
Preliminary test
The TGA-curve of the test item showed that , starting at 275 °C, the weight of the sample decreased significantly. At 302 °C the sample weight had decreased by 25%. After the experiment, a dark brown molten residue remained in the sample container (original colour: white to very pale yellow). The change of the colour indicated reaction and/or decomposition of the test item.
Main study
The DSC-curve obtained with the first experiment showed that an endothermic peak was observed between 100 °C and 150 °C. The extrapolated onset temperature of the peak was 114.95 °C. The effect was most likely obtained due to melting of the test item. An exothermic peak was observed starting at 250 °C. The effect was most likely due to reaction and/or decomposition of the test item. After the experiment, a dark brown molten residue remained in the sample container.
To investigate the melting peak between 100 °C and 150 °C, a repeated heating cycle was applied in the second experiment. With the first heating the extrapolated onset temperature of the peak was 114.74 °C. During cooling no effect was observed due to crystallisation of the test item. With the second heating, no effect was observed due to crystallisation or melting. An exothermic peak was observed starting at 250 °C. The effect was most likely due to reaction and/or decomposition of the test item. After the experiment, a dark brown molten residue remained in the sample container.
In the third experiment, the temperature program was stopped directly after the endothermic peak. The extrapolated onset temperature of the peak was 114.75 °C. After the experiment, a colourless molten residue remained in the sample container. The result demonstrated that the endothermic effect was due to melting of the test item.
Conclusion
The melting temperature of Ethyl Ascorbic acid was determined at 115 °C (388K) by using DSC. During the DSC experiments, reaction and/or decomposition of Ethyl Ascorbic acid was observed starting at 250 °C (523K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.
Applicant's summary and conclusion
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