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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only results were reported.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1973

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
No details on test method
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzophenone
EC Number:
204-337-6
EC Name:
Benzophenone
Cas Number:
119-61-9
Molecular formula:
C13H10O
IUPAC Name:
benzophenone
Details on test material:
- Name of test material (as cited in study report): Benzophenone

Method

Type of population:
not specified
Subjects:
25 volunteers
Route of administration:
dermal
Details on study design:
Benzophenone was tested at a 6% concentration in petrolatum.

Results and discussion

Applicant's summary and conclusion

Conclusions:
No dermal sensitization reactions were observed.
Executive summary:

In a sensitization study (maximization test ) of a 6% solution of benzophenone involving 25 volunteers, no positive reaction was observed.