Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
1979
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Acute toxicity value from secondary literature. Original literature in Russian language only.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Year:
1979
Bibliographic source:
Gigiena i Sanitariya, Vol. 44(12), Pg. 19; cited in database Toxnet; Subdatabase ChemIDPlus; Toxicity data

Materials and methods

Test type:
other: no data

Test material

Constituent 1
Reference substance name:
p-Bromoanisole
IUPAC Name:
p-Bromoanisole

Test animals

Species:
mouse

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 2 200 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Executive summary:

According to a secondary source (via database Toxnet and subdatabase ChemIDPlus), the LD50 of p-Bromoanisole after oral treatment of mice is 2200 mg/ml bw. As the original literature is available in Russian language only and in the secondary source no further information is given, the value of oral toxicity is considered to be not assignable.