2,2,3,3-Tetrafluorooxetane

Additional ecotoxological information

Administrative data

Endpoint:

additional ecotoxicological information

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

9 – 10 March 2010

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Non GLP study and no standard method used (feasibility study)

Cross-reference

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

no guideline required

Principles of method if other than guideline:

Feasibility trial to investigate suitable method for formulation of test media for use in aquatic toxicity testing.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2,2,3,3-tetrafluorooxetane

EC Number:

700-202-5

Cas Number:

765-63-9

Molecular formula:

C3H2F4O

IUPAC Name:

2,2,3,3-tetrafluorooxetane

Details on test material:

- Name of test material (as cited in study report): TFO
- Substance type: organic
- Physical state: liquid
- Analytical purity: 99%
- Lot/batch No.: TFOS285001
- Expiration date of the lot/batch: 30 April 2010
- Storage condition of test material: not reported

Results and discussion

Any other information on results incl. tables

Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.

Applicant's summary and conclusion

Conclusions:

It is proposed that range finding tests are performed under sealed conditions, at nominal concentrations of 0.1, 1, 10 and 100 mg TFO/L, with test media prepared via direct addition of the test material to the dilution media. The time taken for media preparation will be kept to a minimum in an attempt to minimise any losses by volatility.

Executive summary:

Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.