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Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
9 – 10 March 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non GLP study and no standard method used (feasibility study)
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Feasibility trial to investigate suitable method for formulation of test media for use in aquatic toxicity testing.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,3,3-tetrafluorooxetane
EC Number:
700-202-5
Cas Number:
765-63-9
Molecular formula:
C3H2F4O
IUPAC Name:
2,2,3,3-tetrafluorooxetane
Details on test material:
- Name of test material (as cited in study report): TFO
- Substance type: organic
- Physical state: liquid
- Analytical purity: 99%
- Lot/batch No.: TFOS285001
- Expiration date of the lot/batch: 30 April 2010
- Storage condition of test material: not reported

Results and discussion

Any other information on results incl. tables

Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.

Applicant's summary and conclusion

Conclusions:
It is proposed that range finding tests are performed under sealed conditions, at nominal concentrations of 0.1, 1, 10 and 100 mg TFO/L, with test media prepared via direct addition of the test material to the dilution media. The time taken for media preparation will be kept to a minimum in an attempt to minimise any losses by volatility.
Executive summary:

Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.

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