Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed according to OECD 117 and EEC method A8 and in compliance with GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,3,3-tetrafluorooxetane
EC Number:
700-202-5
Cas Number:
765-63-9
Molecular formula:
C3H2F4O
IUPAC Name:
2,2,3,3-tetrafluorooxetane
Details on test material:
- Name: TFO
- Chemical name: 2,2,3,3-Tetrafluorooxetane
- Appearance: Transparent liquid
- Storage conditions: Room temperature
- Lot number: TFOS285001
- Purity: 99%
- Expiry date: 30 April 2010
- Date received: 16 October 2008

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
5.3
Temp.:
25 °C
Remarks on result:
other: pH is not reported

Applicant's summary and conclusion

Conclusions:
TFO was found to have a log10Pow value of 5.3.

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