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EC number: 470-080-3
CAS number: -
The toxicity of 1-((2-Butyloctyloxymethyl)-2-(3,4-dihydro-isoquinolinium-2-yl)ethyl)sulfate towards algae Desmodesmus subspicatus was assesd during 72 hours according OECD guideline 201 and EU method C.3. The 72 hour EC50 values for the test item were 0.136 mg/L EbC50 and > 1.58 mg/L for the ErC50 based on the mean of analytically determined concentrations. The 72 hour NOEC values for the test item were 0.0402 mg/L NOECb and 0.0772 mg/L for theNOECr based on the mean of analytically determined concentrations.
The toxicity of
towards algae Desmodesmus subspicatus was assesd during 72 hours
according OECD guideline 201 and EU method C.3.
The test concentrations of 0, 1.58, 0.803,
0.367, 0.167, 0.0772, 0.0402 mg/L (mean mesured analytical
concentrations) were selected on the basis of the non-GLP range finding
part of the study. The raw data of this part are archived together with
the raw data of this study. The test was performed in concentrations up
to the limit of solubility of the test substance in water. The water
solubility of the test substance is 2.5 mg/L (20°C). The initial
measured concentrations of the saturated solution was 2.88 mg/L and thus
above the water solubility of 2.5 mg/L. During the 72 h testing period a
marked decrease of the test concentrations to 0 - 10 % of the initial
concentrations was observed. Therefore the results are based on the mean
analytically determined concentrations during the exposure period.
The following effect concentrations (mg/L)
were obtained based on mean measured concentrations:
Effect on the development of biomass
(area under the curve):
EbC10 (72 h) = 0.054 mg/L
EbC50 (72 h) = 0.136 mg/L
EbC90 (72 h) > 1.58 mg/L
Effect on growth rate:
ErC10 (72 h) = 0.096 mg/L
ErC50 (72 h) > 1.58 mg/L
ErC90 (72 h) > 1.58 mg/L
No observed effect concentration (95%
NOEC (72 h) = 0.0402 mg/L (biomass)
NOEC (72 h) = 0.0772 mg/L (growth rate)
Lowest observed effect concentration (95%
LOEC (72 h) = 0.0772 mg/L (biomass)
LOEC (72 h) = 0.167 mg/L (growth rate)
Since the analytically determined test
concentrations decreased markedly over the exposure period the test
results were based on mean measured concentrations.
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