Registration Dossier
Registration Dossier
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EC number: 427-900-1 | CAS number: 198404-98-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Study period:
- 1997
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration. - Key result
- Duration:
- 38 d
- Dose descriptor:
- EC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other:
- Remarks:
- OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
- Validity criteria fulfilled:
- yes
- Conclusions:
- OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.
The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.
Reference
Description of key information
In an OECD 301F Ready Biodegradability study two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.
The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
In an OECD 301F Ready Biodegradability study two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.
The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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