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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Justification for type of information:
Experimental study made available by ECHA
Qualifier:
according to
Guideline:
other: 92/69/EEC, C4 (manometric respirometry test)
Principles of method if other than guideline:
To determine percent biodegradation of test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) by using COD as parameter for 28 days.
GLP compliance:
not specified
Oxygen conditions:
not specified
Inoculum or test system:
not specified
Duration of test (contact time):
28 d
Parameter followed for biodegradation estimation:
CO2 evolution
Reference substance:
other: Sodium benzoate
Parameter:
% degradation (CO2 evolution)
Value:
0
Sampling time:
28 d
Details on results:
Points of degradation plot (test substance):
0 % degradation after 5 d
0 % degradation after 7 d
0 % degradation after 14 d
0 % degradation after 21 d
0 % degradation after 28 d
0 % degradation after 38 d
Results with reference substance:
Points of degradation plot (reference substance):
77 % degradation after 5 d
86 % degradation after 7 d
91 % degradation after 10 d
94 % degradation after 14 d
95 % degradation after 21 d
97 % degradation after 28 d
Interpretation of results:
not readily biodegradable
Conclusions:
The test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) showed 0 % biodegradation by using CO2 as parameter in 28 days.Based on percent biodegradability it is concluded that this test chemical is not readily biodegradable.
Executive summary:

Based on available data from secondary source, the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS)  showed 0 % biodegradation by using CO2 as parameter in 28 days.Based on percent biodegradability it is concluded that this test chemical is not readily biodegradable.

Description of key information

Two different experimental studies were reviewed to determine the biodegradability of test chemical in water and their results are summarized below:

 

In first study was based on available data from secondary source,in this the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) showed 0 % biodegradation by using CO2 as parameter in 28 days. On the basis of this percent biodegradability value it is concluded that this test chemical is not readily biodegradable.

 

Further, to support the above study inherent biodegradability study was reviewed from secondary source, in this the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) showed 0 % biodegradation in 48 days. Based on percent biodegradability it is concluded that this test chemical is not inherently biodegradable.

 

By considering results of both the studies mentioned above it is concluded that test chemical is not biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:
freshwater

Additional information

Two different experimental studies were reviewed to determine the biodegradability of test chemical in water and their results are summarized below:

 

In first study was based on available data from secondary source,in this the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) showed 0 % biodegradation by using CO2 as parameter in 28 days. On the basis of this percent biodegradability value it is concluded that this test chemical is not readily biodegradable.

 

Further, to support the above study inherent biodegradability study was reviewed from secondary source, in this the test chemical (1-METHYL-2-(1,2,2-TRIMETHYLBICYCLO(3.1.0)-HEX-3-YLMETHYL)CYCLOPROPYL)METHANOL( MIXTURE OF DIASTEREOISOMERS) showed 0 % biodegradation in 48 days. Based on percent biodegradability it is concluded that this test chemical is not inherently biodegradable.

 

By considering results of both the studies mentioned above it is concluded that test chemical is not biodegradable.