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Environmental fate & pathways

Adsorption / desorption

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 12, 2018 - November 13, 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Version / remarks:
European Commission Regulation (EC) No. 440/2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Radiolabelling:
no
Test temperature:
25°C
Details on study design: HPLC method:
EQUIPMENT
- Apparatus: HPLC System Agilent 1100 series
- Type, material and dimension of analytical (guard) column: commercially available cyanopropyl solid phase containing lipophilic and polar moieties, stainless steel, 5 µM

MOBILE PHASES
- Type: methanol/distilled water
- pH: 6.2

DETERMINATION OF DEAD TIME
- Method: by inert substances which are not retained by the column

REFERENCE SUBSTANCES
- Identity: Acetanilide, Atrazin, Triadimenol, Linuron, Pyrazophos, Diclofop-methyl, 4,4`-DDT

REPETITIONS
- Number of determinations: 2

EVALUATION
- Calculation of capacity factors k': according to OECD TG 121
- Determination of the log Koc value: according to OECD TG 121
Key result
Sample No.:
#1
Type:
log Koc
Value:
3.35 dimensionless
pH:
6.2
Temp.:
25 °C
Key result
Sample No.:
#2
Type:
log Koc
Value:
3.35 dimensionless
pH:
6.2
Temp.:
25 °C
Details on results (HPLC method):
- Average retention data for test substance: retention time = 1.77 (1st measurement), 1.77 (2nd measurement)
Validity criteria fulfilled:
yes
Conclusions:
The log Koc value of the substance was determined according to OECD Guideline 121 and European Commission Regulation (EC) No 440/2008. The adsorption coefficient of the test item was found to be: log Koc = 3.4.
Executive summary:

The log Koc value of the substance was determined according to OECD Guideline 121 and European Commission Regulation (EC) No 440/2008. The HPLC method is based on the correlation between the adsorption coefficient Koc and the retention of a substance on a reversed phase column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. The average retention data for test substance were 1.77 (1st measurement) and 1.77 (2nd measurement). The adsorption coefficient of the test item was found to be: log Koc = 3.4.

Description of key information

The adsorption coefficient of the test item was found to be: log Koc = 3.4 at 25 °C

Key value for chemical safety assessment

Additional information

The log Koc value of the substance was determined according to OECD Guideline 121 and European Commission Regulation (EC) No 440/2008.The HPLC method is based on the correlation between the adsorption coefficient Koc and the retention of a substance on a reversed phase column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties.The average retention data for test substance were 1.77 (1st measurement) and 1.77 (2nd measurement). The adsorption coefficient of the test item was found to be: log Koc = 3.4.