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Physical & Chemical properties

Flammability

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Reference
Endpoint:
flammable solids
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
March 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
1. SOFTWARE
: T.E.S.T

2. MODEL: version
4.2.1

3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
: CCCCC(CC)CNc1ccc2ccccc2c1N=Nc1ccc(N=Nc2cccc(C)c2)c(C)c1

4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
Please see attached QPRF

5. APPLICABILITY DOMAIN
Please see attached QPRF

6. ADEQUACY OF THE RESULT
The result will be used as a weight of evidence approach to support a conclusion that the test substance is not flammable.
Reference:
Composition 0
Qualifier:
according to
Guideline:
other: REACH guidance on QSARS R6
Version / remarks:
Version of May 2008
Principles of method if other than guideline:
An attempt was made to measure the flammability of Solvent Red 500 according to method A10 of regulation 440/2008. The material is a very hard waxy solid. Method A10 is suitable for powdery, granular or paste-like substances, that can be shaped into an unbroken strip. Technically this is not possible with this material.

REACH Annex XI allows for adaptation of certain testing requirements if certain conditions are fulfilled, in particular if testing is technically not possible, and if results from a reliable QSAR method can be used to conclude on a particular end point.
Based on the known structural similarity to other materials, Solvent Red 500 is not expected to be flammable.
A QSAR approach using USA EPA T.E.S.T was used to estimate the flammability.

GLP compliance:
no
Test material information:
Composition 1
Key result
Test procedure:
other: QSAR
Remarks on result:
other: not flammable
Interpretation of results:
not classified based on GHS criteria
Conclusions:
An attempt was made to measure the flammability of Solvent Red 500 according to method A10 of regulation 440/2008. The material is a very hard waxy solid. Method A10 is suitable for powdery, granular or paste-like substances, that can be shaped into an unbroken strip. Technically this is not possible with this material.
A QSAR approach using USA EPA T.E.S.T was used to estimate the flammability.
The conclusion was that the material was not flammable.
Executive summary:

An attempt was made to measure the flammability of Solvent Red 500 according to method A10 of regulation 440/2008.  The material is a very hard waxy solid.  Method A10 is suitable for powdery, granular or paste-like substances, that can be shaped into an unbroken strip.  Technically this is not possible with this material.

REACH Annex XI allows for adaptation of certain testing requirements if certain conditions are fulfilled, in particular if testing is technically not possible, and if results from a reliable QSAR method can be used to conclude on a particular end point.  

Based on the known structural similarity to other materials, Solvent Red 500 is not expected to be flammable.

A QSAR approach using USA EPA T.E.S.T was used to estimate the flammability.

The results was as follows:

QSAR Results using T.E.S.T: Flash point > 400°C  Not flammable

Description of key information

In accordance with section 1 of REACH Annex XI, the flammability (pyrophoric properties and flammability on contact with water) studies (required in section 7.10 of Annex VII) do not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time and experience in production or handling shows that the substance does not react with water.

Due to the physical form of Solvent Red 500, it was found to be technically challenging to test for flammability.

A conclusion on flammability was drawn based on:

A QSAR approach concluding: Not flammable

Read across to an analogue substance concluding: Not flammable

Key value for chemical safety assessment

Flammability:
not classified

Additional information

Justification for classification or non-classification

Based on a weight of evidence from the properties of Solvent Red 19E as an analogue, and using a QSAR approach, it is concluded that the substance Solvent Red 500 is not flammable.