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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February - May 1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method
Test material information:
Composition 1
Key result
Water solubility:
< 3 µg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
> 7 - < 8

The Individual Test and Fraction results are tabulated below:

 Fraction  Test A    Test B  
   conc ug/L  pH  conc ug/L  pH
 1  <3  8.1  <3  7.0
 2  <3  7.4  <3  7.1
 3  <3  7.3  <3  7.2
 4  <3  7.1  <3  7.3
 5  <3  7.3  <3  6.6
 5  <3  6.7  <3  6.6
Conclusions:
The water solubility of the test substance at 20°C and pH 7-8 is <3ug/L. In conclusion the material is insoluble in water.
Executive summary:

The water solubility of the test substance, determined in accordance with the column method as described in EU Method A6 in <3ug/L at 20°C.

In addition, Water solubility value was calculated by WATERNT model (version 1.01) and fragment method: 4.917 × 10^-7 mg/L at 25 °C.

Water solubility value was calculated by WSKOW model (version 1.42): 2.082 × 10^-8 mg/L at 25 °C.

Description of key information

Insoluble. The water solubility of the test substance at 20°C and pH 7-8 is <3ug/L

Key value for chemical safety assessment

Water solubility:
3 µg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test substance, determined in accordance with the column method as described in EU Method A6 in <3ug/L at 20°C