Registration Dossier
Registration Dossier
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EC number: 500-039-8 | CAS number: 25322-69-4 1 - 4.5 moles propoxylated
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Long-term exposure of aquatic invertebrates is not considered relevant as the substance is somewhere between inherently and ready biodegradable, depending on exact composition. Furthermore, the long-term toxicity test with the structural analogues mono- and tripropylene glycol show very low long term toxicity to aquatic invertebrates (7d NOEC of 13020 mg/L to Ceriodaphnia duba and 21d-NOEC of > 1000 mg/L to Daphnia magna, respectively). Based on these results, it can be assumed that the 21d-NOEC of ‘propane-1,2-diol, propoxylated’ is > 100 mg/L. This is supported by calculations with ECOSAR v1.11 which indicate a 16d-ChV of 550-650 mg/L based on modelling of the components and the composition of the multi-constituent substance. Therefore, a long-term toxicity test with aquatic invertebrates is not considered necessary.
Key value for chemical safety assessment
Additional information
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