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Diss Factsheets
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EC number: 430-150-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Environmental fate and pathways:
The registered substance is readily biodegradable and therefore is not persistent. In addition, the log Kow value was determined as 3.32 and therefore the substance is not considered likely to bioaccumulate.
Aquatic toxicity:
One experimental study of reliability 1 (based on international guideline and GLP compliance) and two QSAR results are available to assess the aquatic toxicity of the registered substance, on aquatic invertebrates and algae.
The experimental short-term toxicity study on the aquatic invertebrate, Daphnia magna, was performed on the registered substance. In this study, the 48h-EC50 value, based on analytically confirmed nominal concentrations, was determined to be 30.3 mg/L (95%-Confidence Limit: 28.0 – 32.1 mg/L). This study was supported by a conservative QSAR result on aquatic invertebrates performed on the registered substance also.
The QSAR predictions (iSafeRat holistic approach v1.4) have been validated to be compliant with the OECD recommendations for QSAR modeling (OECD, 2004) and predict the ecotoxicological values which would be expected when testing the substance under experimental conditions in a laboratory following OECD Guidelines. The immobility of the daphnids was determined using a validated QSAR for the Mode of Action in question, (MOA 1, non-polar narcosis) using training sets for which the concentrations of the test substance had been determined by chemical analyses over the test period. The 48h-EC50 value based on mobility of aquatic invertebrates was determined to be 9.2 mg/L (95%-Confidence Limit: 8.4 - 10 mg/L). Based on this data, this QSAR result is considered more conservative than the in vivo result. For the algae endpoint, the iSafeRat QSAR model was validated for use with the same applicability domain and under the same conditions as the daphnid QSAR using a holistic approach. Thus the prediction method can be considered sufficient to assess, in a conservative way, the toxicity of the registered substance to algae. The 72h-ErC50 value based on growth rate of algae was determined to be 8.5 mg/L (95%-Confidence Limit: 7.5 – 9.7 mg/L). An in vivo algae study is therefore not considered necessary.Conclusion on classification
No harmonised classification is available.
1 < lowest EC50 value < 10 mg/L; readily biodegradable; log Kow = 3.32.
Classification according to the Annex VI of the Regulation (EC) No 1272/2008 (CLP): The registered substance is not classified for the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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