Registration Dossier
Registration Dossier
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EC number: 226-164-5 | CAS number: 5307-14-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of test substance 2-nitro-p-phenylenediamine was tested by the well diffusion assay technique against common bacterial species. Aeromonas hydrophila,Escherichia coli,Klebsiella pneumoniae,Pseudomonas fluorescens,Salmonella enteritidis,Shigella sonnei and Streptococcus mitis at dose concentration 300 µg/well.
The test material was dissolved in dimethylsulfoxide. Control diameter is 8 mm.
The growth of the bacterial species was not inhibited by test material at 300 µg/well
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 300
Additional information
The toxicity of test substance 2-nitro-p-phenylenediamine was tested by the well diffusion assay technique against common bacterial species. Aeromonas hydrophila,Escherichia coli,Klebsiella pneumoniae,Pseudomonas fluorescens,Salmonella enteritidis,Shigella sonnei and Streptococcus mitis at dose concentration 300 µg/well.
The test material was dissolved in dimethylsulfoxide. Control diameter is 8 mm.
The growth of the bacterial species was not inhibited by test material at 300 µg/well
Other supporting study from similar experimental data (Source: Environmental Toxicology and Chemistry, Vol. 16, No. 7, pp. 1366–1369, 1997) on Azotobacter vinelandii bacterial species also indicate the same NOEL i.e 300 µg/well.
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