Registration Dossier
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EC number: 200-661-7 | CAS number: 67-63-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The substance was not toxic to algae when tested according to non-specific methods, the substance was determined to possess a 7 day toxicity threshold, approximately equivalent to the LC3, of 1800 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 1 800 mg/L
Additional information
Four studies addressing toxicity to aquatic algae and cyanobacteria are presented in the dossier.
Toxicity to aquatic algae and cyanobacteria.001- scenedesmus – 1980 – key: Acute toxicity to Scenedesmus quadricauda was assessed according to non-specific guidelines and not according to GLP (pre-dates GLP requirements). Algae were exposed to the substance at a range of concentrations in dilution water (1 part v/v of pollutant solution in 2 to 2 x 1014 parts v/v mixture). The toxic effect measured during the assay was the mean extinction over a time period of 7 days. The study was performed under static conditions using 300 mL glass Erlenmeyer flasks, containing 50 mL of test solution with the algal suspension of the preliminary culture having a known adjusted extinction value. Test flasks were stoppered with metal caps, incubated at 27°C, and shaken once each day. The extinction value of monochromatic radiation at 578 nm for a 10-mm layer of algal suspension was determined. The toxicity threshold (approximately equivalent to the LC3) based on mean extinction value was determined to be 1800 mg/L.
Toxicity to aquatic algae and cyanobacteria.002 Scenedesmus – 1976: Acute toxicity to Scenedesmus quadricauda was assessed according to non-specific guidelines and not according to GLP (pre-dates GLP requirements). Algae were exposed to the substance under static conditions for 8 days. The toxicity threshold based on growth inhibition was determined to be 1800 mg/L. This lower toxicity over a shorter exposure period is in keeping with the result of the key study.
Toxicity to aquatic algae and cyanobacteria.003 – Microcystis – 1978: Acute toxicity to Microcystis aeruginosa was assessed according to non-specific guidelines and not according to GLP (pre-dates GLP requirements). Algae were exposed to the substance under static conditions for 8 days. The toxicity threshold based on growth inhibition was determined to be 1000 mg/L. This lower toxicity over a shorter exposure period is in keeping with the result of the key study.
Toxicity to aquatic algae and cyanobacteria.004 – Scenedesmus – 1978: Acute toxicity to Scenedesmus quadricauda was assessed according to non-specific guidelines and not according to GLP (pre-dates GLP requirements). Algae were exposed to the substance under static conditions for 8 days. The toxicity threshold based on growth inhibition was determined to be 1800 mg/L. This lower toxicity over a shorter exposure period is in keeping with the result of the key study.
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