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Diss Factsheets
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EC number: 203-457-6 | CAS number: 107-05-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: The acute toxicity was tested in accordance with a standardised test system, which did, however, not sufficiently account for the volatility of the test substance. The results are considered as not reliable.
Data source
Reference
- Reference Type:
- publication
- Title:
- Befunde der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna
- Author:
- Bringmann G and Kühn R
- Year:
- 1 977
- Bibliographic source:
- Z f Wasser und Abwasserforschung 10(5), 161-166
Materials and methods
- Principles of method if other than guideline:
- The toxicity of the test material to Daphnia magna was assessed in a 24-hour static test in three parallel test series with at least three tested concentrations (details on concentration not provided, dilutions were prepared in the ratio 1:2).
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-chloropropene
- EC Number:
- 203-457-6
- EC Name:
- 3-chloropropene
- Cas Number:
- 107-05-1
- Molecular formula:
- C3H5Cl
- IUPAC Name:
- 3-chloroprop-1-ene
- Details on test material:
- no data
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- no data
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Wild-caught Daphnia were used in the test and the subject with the highest reproduction rate was chosen for the definite test. Animals were held in ap water and fed green algae. Daphnia were held in 2-litre beakers placed on white desks with at least 12 hours daytime (diffuse day light, artificial light if necessary).
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
- Post exposure observation period:
- no
Test conditions
- Hardness:
- 16 ° (Germany)
- Test temperature:
- 20 to 22 °C
- pH:
- 7.6 to 7.7
- Dissolved oxygen:
- saturated
- Salinity:
- no data
- Nominal and measured concentrations:
- no details
- Details on test conditions:
- The test was performed in 50 mL beakers filled with 20 mL liquid. Ten 24-h old Daphnia were placed in each beaker and the vessels were covered with paper. The test was carried out for 24 hours with no artificial light and no direct sunlight.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Remarks:
- Loss of ability to swim
- Effect conc.:
- 250 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 24 h
- Dose descriptor:
- LC0
- Remarks:
- Loss of ability to swim
- Effect conc.:
- 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 24 h
- Dose descriptor:
- LC100
- Remarks:
- Loss of ability to swim
- Effect conc.:
- 125 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Details on results:
- no data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 value (based on immobility of test animals) for 3-chloropropene determined in a static 24-hour test with Daphnia magna was 250 mg/L.
- Executive summary:
The acute toxicity of 3-chloropropene to Daphnia magna was investigated in a standardised 24-hour static test under controlled conditions. The LC50 value (based on immobility of test animals) was 250 mg/L and the LC0 and LC100 values for the same endpoint were 125 and 500 mg/L, respectively.
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