Registration Dossier
Registration Dossier
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EC number: 201-853-3 | CAS number: 88-72-2
Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity, other
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- other: EU Risk Assessment
- Rationale for reliability incl. deficiencies:
- other: No reliability is given as this is a summary entry for the EU RAR.
- Principles of method if other than guideline:
- EU Risk Assessment
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Analytical purity: not specified
- Executive summary:
EU Risk Assessment (2008):
The only available Data Set information on sediment organisms includes a single datum on the effect of 2-nitrotoluene on Tubifex sp. The EC50 obtained for this organism is higher than the other for the aquatic invertebrates. For the oligochaeta Tubifex sp., 2 -nitrotoluene has shown a 24-h LC50 of 410 mg/l and 48 -h LC50 of 370 mg/l (these results must be considered under the light of the fact that the mortality in the control was above 10%) (Yoshioka et al., 1986b). (It was not possible to validate this information, since only the abstract was provided in English, and so, even the exposure route could not be determined appropriately).
No data have been provided regarding toxicity on marine sediment organisms.
Reference
Description of key information
For transported isolated intermediates according to REACh, Article 18, this endpoint is not a data requirement. However, data is available for this endpoint and is thus reported under the guidance of "all available data".
EU Risk Assessment (2008):
The only available Data Set information on sediment organisms includes a single datum on the effect of 2-nitrotoluene on Tubifex sp. The EC50 obtained for this organism is higher than the other for the aquatic invertebrates. For the oligochaeta Tubifex sp., 2 -nitrotoluene has shown a 24-h LC50 of 410 mg/l and 48 -h LC50 of 370 mg/l (these results must be considered under the light of the fact that the mortality in the control was above 10%) (Yoshioka et al., 1986b). (It was not possible to validate this information, since only the abstract was provided in English, and so, even the exposure route could not be determined appropriately).
No data have been provided regarding toxicity on marine sediment organisms.
Key value for chemical safety assessment
Additional information
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