Registration Dossier
Registration Dossier
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EC number: 603-931-6 | CAS number: 135800-37-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects observed up to the limit of water solubility.
Key value for chemical safety assessment
Additional information
Several long-term freshwater studies on Daphnia magna according to OECD 202 are available for the SCAE C2 -C8 category. No effects were observed up to the limit of water solubility and a NOEC(21 d) > 1 mg/L could be stated.
The key study on long-term toxic effetcs of Fatty acids, C8-16, 2-ethylhexyl esters on Daphnia magna was conducted according to OECD 202 under GLP conditions (Wierich 1998). 1 and 100 mg/L test substance were both tested as filtered test solutions. In the filtered solution of 1 mg/L no effects on Daphnia magna were observed for mortality and reproduction, on the other hand, in the filtered solution of 100 mg/L a significant reduction of the reproduction was stated. The authors supposed that the effects in the 100 mg/L filtered test solution are due to a better water soluble by-compound (for example a short chain fatty acid ester) or - less likely due to a toxic impurity. Therefore, a NOEC(21 d, reproduction) of > 1 mg/L (nominal) was given.
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