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EC number: 252-471-9 | CAS number: 35265-04-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
In the test conditions, 2-(sec-butylamino)ethanol presented no inherent, primary biodegradability.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The aerobic biodegradation of 2-(sec-butylamino)ethanol has been assessed during 28 days according to the OECD 301F guideline and GLP requirements (Feil, 2009). Based on the ThOD(NH4) the percentage biodegradation of 2-(sec-butylamino)ethanol reached 12% (mean) after 28 days of incubation. Taking the occurrence of nitrification into account 2-(sec-butylamino)ethanol reached a percentage biodegradation of 9% (mean). The substance was considered as not readily biodegradable. All the validity criteria were fulfilled. Another biodegradation test according to OECD 310 and GLP requirements has been performed (Xiaoqian, 2012). No degradability of the test substance was observed during the test.
In addition, the study of inherent biodegradation of 2 -(sec-butylamino)ethanol was performed by the modified MITI Test (II) according to OECD 302C and GLP requirements (Xiaoqian, 2011). The calculated percentage biodegradation of 2-[(1-methylpropyl)amino]ethanol based on the BOD was 8.71% in the 28th day. It showed that this test substance has no ultimate biodegradability. The percentage primary biodegradation of test substance in the 28th day was 1.16% based on the calculated results of UPLC-MS analysis. The test substance has no primary biodegradability (no change in molecular structure). According to the cumulative oxygen consumption, the mean degradation percentages of the reference substance were 70.30 % and 72.73 % after 7 and 14 days, respectively. Hence, the test is considered to be valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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