Registration Dossier
Registration Dossier
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EC number: 252-471-9 | CAS number: 35265-04-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Neither mortality nor sublethal effects of rainbow trout were observed at the only test concentration of 4.5 mg/L after 96h of exposure. In addition, the threshold levels of lethal and other observed effects for Gobiocypris rarus exposed during 14d were determined to be higher than 100 mg/L.
Therefore, the 14d LC50 value was determined to be > 100 mg test item/L.
Key value for chemical safety assessment
Additional information
Acute toxicity of 2-[(1-methylpropyl)amino]ethanol to Oncorhynchus mykiss has been investigated through OECD Guideline 203 and according to GLP requirements in a static 96h test (Kuhl, 2010). In the control and the only test concentration of 4.50 mg test item/L, all fish survived until the end of the experiment and showed no sublethal effects during the exposure time. The concentrations were maintained throughout the test and all the validity criteria were fulfilled.
Moreover, the prolonged toxicity of 2 -[(1 -methylpropyl)amino]ethanol to Gobiocypris rarus has been investigated through OECD guideline 204 and according to GLP requirements in a semi-static test ( Xiaoqian, 2011). The nominal concentrations of the treatment groups were 1.0, 3.2, 10, 32 and 100 mg/L. Under test conditions, the threshold levels of lethal and other observed effects were higher than 100 mg/L. The concentrations were maintained throughout the test and all the validity criteria were fulfilled.
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