Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 406-260-5 | CAS number: 58834-75-6 BTN; VPO CATALYST
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Delayed dermal sensitisation has been investigated using the Maximisation test of Magnusson and Kligman and following OECD/EU test methods. 55% of animals challenged with the substance at a concentration of 50% w/v displayed a significant response. No such reaction was observed in similarly challenged controls. No significant response was observed amongst test or control animals challenged with the substance at a concentration of 10% w/v. It was concluded that the substance causes delayed contact hypersensitivity in guinea-pigs.
Migrated from Short description of key information:
Skin sensitisation: Positive
Justification for classification or non-classification
Classification as a skin sensitiser is justified based on the positive outcome of an in-vivo test.
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