Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

The currently available data do not allow for a definite conclusion on genetic toxicity and further tests may be required.

In an Ames test with Salmonella typhimurium TA 1535, TA 1537, TA 98 and TA 100, and with E. Coli WP2 uvr A, the test substance shows no evidence of mutagenic activity.

In a chromosome aberration study with human lymphocytes in vitro, the test substance was considered to be non-clastogenic.


Short description of key information:
In vitro data from an Ames test and a chromosome aberration test are currently available. The tests were performed according to OECD guidelines and GLP. The substance is considered non-mutagenic in the Ames test and non-clastogenic in human lymphocyte cells.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Based on the currently available data, i.e. in vitro data, definite conclusions for classification on genotoxicity according to the CLP Regulation (EC) 1272/2008 and Council Directive 67/548/EEC (DSD) cannot be drawn.