Registration Dossier
Registration Dossier
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EC number: 208-831-2 | CAS number: 542-85-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- A QSAR model was used to estimate the EC50 for ethyisothiocyanate and was published as an attachment
Data source
Reference
- Reference Type:
- publication
- Title:
- Ethylisothiocyanate - Short term aquatic toxicity on algae
- Author:
- Schultz,
- Year:
- 1 996
- Bibliographic source:
- Bull Environ Toxicol (1996], 56, 638 – 642
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- Quantitative and qualitative structure-activity relationships (QSARs)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ethyl isothiocyanate
- EC Number:
- 208-831-2
- EC Name:
- Ethyl isothiocyanate
- Cas Number:
- 542-85-8
- Molecular formula:
- C3H5NS
- IUPAC Name:
- ethyl isothiocyanate
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3 720 mg/L
- Nominal / measured:
- not specified
- Remarks on result:
- other: based on LogEC50
- Key result
- Duration:
- 96 h
- Dose descriptor:
- other: Log EC50
- Effect conc.:
- 1.63 mmol/L
- Nominal / measured:
- not specified
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Ethylisothiocyanate is expected to be non toxic to aquatic algae based on a QSAR study
- Executive summary:
Ethylisothiocyanate is expected to be non toxic to aquatic algae based on a QSAR study
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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