Registration Dossier
Registration Dossier
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EC number: 202-908-4 | CAS number: 101-02-0
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- ECC Directive 92/69, A.6
- GLP compliance:
- yes
- Type of method:
- column elution method
Test material
- Reference substance name:
- Triphenyl phosphite
- EC Number:
- 202-908-4
- EC Name:
- Triphenyl phosphite
- Cas Number:
- 101-02-0
- Molecular formula:
- C18H15O3P
- IUPAC Name:
- triphenyl phosphite
- Details on test material:
- - Substance type: organic
- Physical state: liquid
- Lot/batch No.: AAD-Nr. 1473
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 93 µg/L
- Conc. based on:
- test mat. (total fraction)
- Temp.:
- 20 °C
- pH:
- >= 7 - <= 8.7
- Remarks on result:
- other: SD= ±10 µg/L
- Details on results:
- Since the results at the two flow rates are constant within the requirements of the guideline (better than ±30 %) and equivalent within the statistical error the final result can be stated as the mean value of both flow rates (samples 7 to 23, rounded): 93±10 µg/L at 20°C
Remark: The water solubility of test item may be slightly influenced by the presence of its oxidation product, test item phospate, which is formed during the experiment due to the presence of oxygen. In the samples used for evaluation the concentration of the phospate was between 57 and 71 µg/L.
For the calculation of the water solubility only the phosphite (test item) peak areas were used.
Applicant's summary and conclusion
- Conclusions:
- The water solubility of test substance was determined to be 93±10 µg/L at 20°C, pH 7-8.7
The water solubility of test item may be slightly influenced by the presence of its oxidation product, corresponding phosphate, which is formed during the experiment due to the presence of oxygen. For the calculation of the water solubility only the phosphite (test item) peak areas were used.
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