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EC number: 268-750-3
CAS number: 68134-38-3
Skin irritation: not irritant
Eye irritation: eye damage
In a primary dermal irritation study (OECD guideline 404), three male New Zealand white rabbits were dermally exposed to 0.5 g of the test item for 4 hours to a body surface area of 8 cm² under semi-occlusive conditions. Animals then were observed for 1, 24, 48, 72 hours and 8 days and irritation was scored by the method of Draize. The test substance did not cause any skin effects and is considered under the conditions of this study as not irritating to the skin.
In a primary eye irritation study, 0.1 mL of the test item was instilled into the conjunctival sac of one eye of each of three male New Zealand White rabbits. The animals were observed for a period of 8 days. In this study, the test item is corrosive to the eye based on effects on conjunctivae, cornea and iris.
Based on the results of the test performed on BY29 and similar substances, the following classification is required: Eye damage 1, H318.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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