Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-carboxylate

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 02 May 2016 to 24 June 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2016

Report date:

2016

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

2009

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: isothermal thermogravimetry

Test material

Test material information

Constituent 1

Reference substance name:

Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-carboxylate

EC Number:

245-048-5

EC Name:

Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-carboxylate

Cas Number:

22509-74-6

Molecular formula:

C11H9NO4

IUPAC Name:

ethyl 1,3-dioxo-2,3-dihydro-1H-isoindole-2-carboxylate

Test material form:

solid

Details on test material:

- Appearance: white solid
- Storage conditions of test material: in refrigerator (2-8°C)

Specific details on test material used for the study:

Melting point: 79°C

Results and discussion

Vapour pressure

Vapour pressure 1

Key result

Temp.:

25 °C

Vapour pressure:

<= 0.006 Pa

Remarks on result:

other: Weight losses were obtained at temperatures above the melting temperature of 79°C. The vapour pressure at 20/25°C is considered slightly overestimated and therefore reported as a limit value.

Vapour pressure 2

Temp.:

20 °C

Vapour pressure:

<= 0.003 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test substance)

 

Temperature [°C]	Weight loss [µg/min]	¿T [g/cm2/h]	log ¿T	log PT	PT [Pa]
100	5.763	6.88E-04	-3.16	0.94	8.8
	5.444	6.50E-04	-3.19	0.91	8.2
110	10.96	1.31E-03	-2.88	1.26	18
	10.47	1.25E-03	-2.90	1.24	17
120	20.69	2.47E-03	-2.61	1.58	38
	19.28	2.30E-03	-2.64	1.54	35
130	38.34	4.58E-03	-2.34	1.88	76
	34.67	4.14E-03	-2.38	1.83	68

Applicant's summary and conclusion

Conclusions:

The vapour pressure of the substance Carbaethoxyphthalimid at 25°C was determined to be = 0.0061 Pa.

Executive summary:

The vapour pressure of the substance Carbaethoxyphthalimid was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950. The weight losses were obtained with a temperature program above the melting temperature. Vapour pressures extrapolated to 20°C and 25°C could therefore be slightly overestimated and are therefore reported as a limit value. From duplicate measurements, the vapour pressure at 25°C was determined to be 0.0061 Pa and reported as = 0.0061 Pa.The vapour pressure at 20°C was determined to be 0.0033 Pa and reported as = 0.0033 Pa.